The target audience is what it is all about.
Every aspect of the interview process should be designed to appeal to the target audience of the show you are doing the interview for. You need to spend a great deal of time studying what your target audience is interested in. What do they like, who do they like, what do they want to know, what do they care about, what is their passion? This is a very difficult process because chances are, you are not at all like you target audience in terms of your personal interests, so you cannot use your own tastes when making any decision regarding interview subjects, guests, etc. Know the demographics and psychographics of your target audience. By keeping a tightly targeted show, you will also make it easier for the Sales Department to sell time on your show, and the Program Director will be able to keep the show on target for its audience slot. . Do you have any information as to what your target audience wants to learn? New information is generally always better than information that the audience already knows, but perhaps you can put a different spin on the old information. And lets face it, sometimes the audience is happy just watching or listening to the guest, no matter what they say, particularly in the case of entertainment type shows.
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If you have shows that are similar or compete with your show, study the ratings of shows that had guests you are considering interviewing. This can lead you to the guest, type of guest or topic your target audience is interested in. And of course do this same research into your own shows.
Perhaps you would like to share some of the ways you determine who your target audience is interested in?